校徽
Liu Research Group

Biomaterials and Translational Medicine Lab

2020

  • 42.Feng Wu, Yan Pang*, Jinyao Liu*, Swelling-strengthening hydrogels by embedding with deformable nanobarriers. Nature Communications 2020, revised.

  • 41.Zhenping Cao, Jinyao Liu*, Bacteria and bacterial derivatives as drug carriers for cancer therapy. Journal of Controlled Release 2020, accepted.

  • 40.Pingping Feng, Zhenping Cao, Xinyue Wang, Juanjuan Li, Jinyao Liu*, On-demand bacterial reactivation by restraining within a triggerable nanocoating. Advanced Materials 2020, 2002406. In press.

  • 39.Xinyue Wang, Zhenping Cao, Mengmeng Zhang, Lu Meng, Zunzhen Ming, Jinyao Liu*, Bioinspired oral delivery of gut microbiota by self-coating with biofilms. Science Advances 2020, 6, eabb1952.

  • 38.Zunzhen Ming, Yan Pang, Jinyao Liu*, Switching between elasticity and plasticity by network strength competition. Advanced Materials 2020, 1906870.

  • 37.Ke Liu, Cong Xu, Jinyao Liu*, Regulation of cell binding and entry by DNA origami mediated spatial distribution of aptamers. Journal of Materials Chemistry B 2020, DOI: 10.1039/d0tb00663g.

  • 36.Yuan Hu, Huaimin Wang, Chenge Li, Jinyao Liu*, Bing Xu*, Wen Di*, Enzyme-instructed assembly of a cholesterol conjugate promotes pro-inflammatory macrophages and induces apoptosis of cancer cells. Biomaterials Science 2020, 8, 2007.

  • 35.Zunzhen Ming, Yan Pang, Jinyao Liu*, Mechanical deformation mediated transmembrane transport. Macromolecular Rapid Communications 2020, 1900518.

2019

  • 34.Zhenping Cao#, Xinyue Wang#, Yan Pang, Shanshan Cheng, Jinyao Liu*, Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment. Nature Communications 2019, 10(5783), 1-11.

  • 33.Zhenping Cao, Shanshan Cheng, Xinyue Wang, Yan Pang*, Jinyao Liu*, Camouflaging bacteria by wrapping with cell membranes. Nature Communications 2019, 10(3452), 1-10. (Featured by Nature Communications Editors' Highlights)

  • 32.Yan Pang, Jinyao Liu, Zaina L Moussa, Joy E Collins, Shane McDonnell, Alison M Hayward, Robert Langer, Giovanni Traverso*, Endoscopically-injectable shear-thinning hydrogels facilitating polyp removal. Advanced Science 2019, 1901041.

2017

  • 31.Jinyao Liu, Yan Pang, Shiyi Zhang, Cody Cleveland, Xiaolei Yin, Lucas Booth, Jiaqi Lin, Young-Ah Lucy Lee, Hormoz Mazdiyasni, Thomas von Erlach, Jaimie Rogner, Robert S. Langer*, Giovanni Traverso*, Triggerable tough hydrogels for gastric resident dosage forms. Nat. Commun. 2017, 8, 124. Featured by MIT News, Boston Herald.

  • 30.Jayanta Bhattacharyya, Isaac Weitzhandler, Shihan Bryan Ho, Jonathan R. McDaniel, Xinghai Li, Lei Tang, Jinyao Liu, Mark Dewhirst, Ashutosh Chilkoti*, Encapsulating a hydrophilic chemotherapeutic into rod-like nanoparticles of a genetically encoded asymmetric triblock polypeptide improves its efficacy. Adv. Funct. Mater. 2017, 27, 1605421.

2016

  • 29.Yan Pang,# Jinyao Liu,# Yizhi Qi,# Xinghai Li, Ashutosh Chilkoti*, A modular method for the high-yield synthesis of site-specific protein-polymer therapeutics. Angew. Chem., Int. Ed. 2016, 55, 10296. Published as a Very Important Paper (VIP).

  • 28.Jinyao Liu, Yan Pang, Jayanta Bhattacharyya, Wenge Liu, Isaac Weitzhandler, Xinghai Li, Ashutosh Chilkoti*, Developing precisely defined drug-loaded nanoparticles by ring-opening polymerization of a paclitaxel prodrug. Adv. Healthcare Mater. 2016, 5, 1868.

2015

  • 27.Jinyao Liu, Wei Huang*, Yan Pang, Deyue Yan*, Hyperbranched polyphosphates: synthesis, functionalization and biomedical applications. Chem. Soc. Rev. 2015, 44, 3942.

  • 26.Somnath Bhattacharjee, Wenge Liu, Wei-Han Wang, Isaac Weitzhandler, Xinghai Li, Yizhi Qi, Jinyao Liu, Yan Pang, Donald F Hunt, Ashutosh Chilkoti*, Site-specific zwitterionic polymer conjugates of a protein have long plasma circulation. ChemBioChem 2015, 16, 2451.

  • 25.Jinyao Liu, Wenge Liu, Isaac Weitzhandler, Jayanta Bhattacharyya, Xinghai Li, Jing Wang, Yizhi Qi, Somnath Bhattacharjee, Ashutosh Chilkoti*, Ring-opening polymerization of prodrugs: A versatile approach to prepare well-defined drug loaded nanoparticles. Angew. Chem., Int. Ed. 2015, 54, 1002.

2013

  • 24.Jinyao Liu,# Yan Pang,# Zhaoyang Zhu, Dali Wang, Chunting Li, Wei Huang*, Xinyuan Zhu, Deyue Yan*, Therapeutic nanocarriers with hydrogen peroxide-triggered drug release for cancer treatment. Biomacromolecules 2013, 14, 1627. One of the Most Read articles in 04/2013.

2012

  • 23.Jinyao Liu, Yan Pang*, Jun Chen, Ping Huang, Wei Huang*, Xinyuan Zhu, Deyue Yan*, Hyperbranched polydiselenide as a self assembling broad spectrum anticancer agent. Biomaterials 2012, 33, 7765.

  • 22.Xiaohua Huang, Wei Huang*, Jinyao Liu, Lili Meng, Deyue Yan*, Synthesis of highly soluble and transparent polyimides. Polym. Int. 2012, 61, 1503.

  • 21.Dali Wang, Xiuying Huan, Lijuan Zhu, Jinyao Liu, Feng Qiu, Deyue Yan, Xinyuan Zhu*, Salt/pH dual-responsive supramolecular brush copolymer micelles with molecular recognition of nucleobases for drug delivery. RSC Adv. 2012, 2, 11953.

2011

  • 20.Jinyao Liu, Wei Huang*, Yan Pang, Ping Huang, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Molecular self-assembly of a homopolymer: An alternative to fabricate drug delivery platform for cancer therapy. Angew. Chem., Int. Ed. 2011, 50, 9162.

  • 19.Jinyao Liu,# Yan Pang,# Wei Huang*, Zhaoyang Zhu, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Redox responsive polyphosphate nanosized assemblies: A smart drug delivery platform for cancer therapy. Biomacromolecules 2011, 12, 2407. One of the Most Read articles in 06/2011.

  • 18.Jinyao Liu,# Yan Pang,# Wei Huang*, Xiaohua Huang, Lili Meng, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Bioreducible micelles self-assembled from amphiphilic hyperbranched multiarm copolymer for glutathione-mediated intracellular drug delivery. Biomacromolecules 2011, 12, 1567. Highlighted on the homepage of Biomacromolecules and one of the Most Read articles in 05/2011.

  • 17.Yan Pang,# Jinyao Liu,# Yue Su, Jieli Wu, Lijuan Zhu, Xinyuan Zhu*, Deyue Yan, Bangshang Zhu*, Design and synthesis of thermo-responsive hyperbranched poly(amine-ester)s as acid-sensitive drug carriers. Polym. Chem. 2011, 2, 1661. Front cover page article and highlighted by Polymer Chemistry Blog in 06/2011.

  • 16.Guolin Li,# Jinyao Liu,# Yan Pang, Ruibin Wang, Limin Mao, Deyue Yan, Xinyuan Zhu*, Jian Sun*, Polymeric micelles with water-insoluble drug as hydrophobic moiety for drug delivery. Biomacromolecules 2011, 12, 2016. One of the Most Read articles in 06/2011.

  • 15.Xiang Zhai, Wei Huang*, Jinyao Liu, Yan Pang, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan, Micelles from amphiphilic block copolyphosphates for drug delivery. Macromol. Biosci. 2011, 11, 1603.

  • 14.Yan Pang, Qi Zhu, Dongliang Zhou, Jinyao Liu, Yan Chen, Yue Su, Deyue Yan, Xinyuan Zhu*, Bangshang Zhu*, Synthesis of backbone thermo and pH dual-responsive hyperbranched poly(amine-ether)s through proton-transfer polymerization. J. Polym. Sci.: Part A: Polym. Chem. 2011, 49, 966.

  • 13.Dali Wang, Yue Su, Chengyu Jin, Bangshang Zhu, Yan Pang, Lijuan Zhu, Jinyao Liu, Chunlai Tu, Deyue Yan, Xinyuan Zhu*, Supramolecular copolymer micelles based on the complementary multiple hydrogen bonds of nucleobases for drug delivery. Biomacromolecules 2011, 12, 1370.

2010

  • 12.Jinyao Liu, Wei Huang*, Yan Pang, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers. Biomaterials 2010, 31, 5643.

  • 11.Jinyao Liu,# Yan Pang,# Wei Huang*, Xiang Zhai, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Controlled topological structure of copolyphosphates by adjusting pendant groups of cyclic phosphate monomers. Macromolecules 2010, 43, 8416.

  • 10.Jinyao Liu, Wei Huang*, Yan Pang, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Hyperbranched polyphosphates for drug delivery application: Design, synthesis, and in vitro evaluation. Biomacromolecules 2010, 11, 1564. One of the Most Read articles in 05/2010.

  • 9.Jinyao Liu, Wei Huang*, Yan Pang, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Self-assembled micelles from an amphiphilic hyperbranched copolymer with polyphosphate arms for drug delivery. Langmuir 2010, 26, 10585.

  • 8.Yan Pang,# Jinyao Liu,# Jieli Wu, Guolin Li, Ruibin Wang, Yue su, Xinyuan Zhu*, Deyue Yan, Bangshang Zhu*, Synthesis, characterization, and in vitro evaluation of long-chain hyperbranched poly(ethylene glycol) as drug carrier. Bioconjugate Chem. 2010, 21, 2093. One of the Most Read articles in 10/2010.

  • 7.Yan Pang, Jinyao Liu, Yue Su, Bangshang Zhu, Wei Huang, Yongfeng Zhou, Xinyuan Zhu*, Deyue Yan*, Bioreducible unimolecular micelles based on amphiphilic multiarm hyperbranched copolymers for triggered drug release. Sci. China Chem. 2010, 53, 2497. Front cover page article.

  • 6.Yongfeng Zhou, Wei Huang, Jinyao Liu, Xinyuan Zhu*, Deyue Yan*, Self-assembly of hyperbranched polymers and its biomedical applications. Adv. Mater. 2010, 22, 4567.

  • 5.Yan Pang, Qi Zhu, Jinyao Liu, Jieli Wu, Ruibin Wang, Suyun Chen, Xinyuan Zhu*, Deyue Yan, Wei Huang, Bangshang Zhu*, Design and synthesis of cationic drug carriers based on hyperbranched poly(amine-ester)s. Biomacromolecules 2010, 11, 575.

  • 4.Yan Chen, Yan Pang, Jieli Wu, Yue Su, Jinyao Liu, Ruibin Wang, Bangshang Zhu, Yefeng Yao, Deyue Yan, Xinyuan Zhu*, Qun Chen*, Controlling the particle size of interpolymer complexes through host-guest interaction for drug delivery. Langmuir 2010, 26, 9011.

  • 3.Jinyao Liu, Yan Pang, Wei Huang*, Xinyuan Zhu, Yongfeng Zhou, Deyue Yan*, Self-assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery. Biomaterials 2010, 31, 1334. Highlighted by “Noteworthy Chemistry” of ACS.

2009

  • 2.Jinyao Liu, Wei Huang*, Yongfeng Zhou, Deyue Yan*, Synthesis of hyperbranched polyphosphates by self-condensing ring-opening polymerization of HEEP without catalyst. Macromolecules 2009, 42, 4394.

2008

  • 1.Jinyao Liu, Zhihua Nie, Yong Gao, Alex Adronov, Huaming Li*, “Click’’ coupling between alkyne-decorated multi-walled carbon nanotubes and reactive PDMA-PNIPAM micelles. J. Polym. Sci.: Part A: Polym. Chem. 2008, 46, 7187.

Patents

  • 7.Robert Langer, Giovanni Traverso, Jinyao Liu, Yan Pang, Injectable shear-thinning hydrogels and uses thereof, U.S. patent, 2020. 4. 24, No. 16/857279

  • 6.Robert Langer, Giovanni Traverso, Jinyao Liu, Yan Pang, Injectable shear-thinning hydrogels and uses thereof, WIPO patent, 2020.4.24, No. PCT/US20/29767

  • 5.Jinyao Liu, Yan Pang, Zhenping Cao, Xinyue Wang, Coated bacteria and the applications, China patent, 2019.11.3, No. 201911034435.7

  • 4.Robert Langer, Giovanni Traverso, Jinyao Liu, Yan Pang, Endoscopically-injectable shear-thinning hydrogels facilitating polyp removal, U.S. patent, 2019. 6. 24, No. 62/865472

  • 3.Giovanni Traverso, Jinyao Liu, Robert Langer, Triggerable hydrogel compositions and related methods, WIPO patent, 2017.11.9, No. PCT/US2017/060932

  • 2.Giovanni Traverso, Jinyao Liu, Robert Langer, Triggerable tough hydrogels for gastric resident dosage forms, U.S. patent, 2016.11.9, No. 62/419650

  • 1.Jinyao Liu, Wei Huang, Deyue Yan, Synthesis of biocompatible and biodegradable hyperbranched polyphosphates by self-condensing ring-opening polymerization, China patent, 2009, CN101585919

Patents

Peer-reviewed papers